The Consultation on Strategic Information and HIV Prevention among Most-at-Risk Adolescents (MARA) focused on experiences in countries where HIV infection is concentrated among men who have sex with men (MSM), injecting drug users (IDUs), and those who sell sex. The meeting facilitated the exchange of information across regions on country-level data collection regarding MARA; identified ways to use strategic information to improve HIV prevention among MARA; and suggested ways to build support for MARA programming among decision-makers.