Despite growing interest in undertaking research in adolescent HIV, the current pace of interventional research in particular remains very low compared with the needs of adolescents living with HIV(ALHIV). More robust evidence is needed to inform innovative and targeted interventions that bridge research gaps, inform policy, and improve outcomes for adolescents. Armstrong et al. document a global research prioritization exercise that was undertaken by WHO and CIPHER to focus efforts on priority research in the context of diminishing resources (2018).