USAID/Guinea contracted YouthPower2: Learning and Evaluation to conduct a cross-sectoral youth assessment (CSYA) to help in identifying opportunities for a more strategic engagement of youth in shaping Guinea’s journey to self-reliance. This CSYA aimed to capture the experiences, aspirations, challenges, and assets of Guinean youth ages 15-35 and to identify effective programs, organizations, and partnerships supporting youth to reach their full potential. USAID/Guinea will use the findings from this assessment to inform its youth approach by working in greater alignment with the Positive Youth Development (PYD) framework. The findings and recommendations outlined below are based on the primary and secondary data obtained from research conducted between March and May 2020 that included 21 key informant interviews (KIIs) and 20 youth-led focus group discussions with 125 youth in the eight administrative regions of Guinea: Boké, Conakry, Faranah, Kankan, Kindia, Labé, Mamou, and Nzérékoré. Due to COVID-19 restrictions, some data was collected in-person and some remotely.